What is the difference between the Pap test and a colposcopy and biopsy?
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The Pap test involves the collection of a random cell specimen from the cervical surface and the endocervical canal. If the physician detects any abnormal cells during the ensuing microscopic examination, it is hard to know the exact location they came from.

A biopsy provides an accurate diagnosis if it is taken from the right site. Finding the right site for a biopsy requires a colposcopy, which must be performed by a specialized physician. Otherwise, the biopsy might be taken from the wrong site and produce misleading results.